基于组合双向拍卖的云资源调度方法

针对跨数据中心的资源调度问题，提出了一种基于组合双向拍卖（PCDA）的资源调度方案。首先，将云资源拍卖分为三个部分：云用户代理报价、云资源提供商要价、拍卖代理组织拍卖；其次，在定义用户的优先级及任务紧迫度的基础上，在拍卖过程中估算每一个工作发生的服务等级协议（SLA）违规并以此计算云提供商的收益，同时每轮竞拍允许成交多项交易；最终达到根据用户等级合理分配云资源调度的效果。仿真实验结果表明该算法保证了竞拍成功率，与传统一次拍卖成交一项的组合双向拍卖方案相比，PCDA在竞拍时间段产生的能耗降低了35.00%，拍卖云提供商的利润提高了约38.84%。     

Enumeration of stereo,position and chiral isomers of polysubstituted giant fullerenes: applications to C180 and C240

Abstract

We have developed combinatorial generation function methods that combine M?bius inversion and character cycle indices for the enumeration of stereo, position and chiral isomers of icosahedral giant fullerenes C₁₈₀ and C₂₄₀. Techniques are also developed for the machine perception of symmetries of especially giant fullerenes. The techniques yield, symmetries, position, stereo and chiral isomers of giant fullerenes which we illustrate with applications to icosahedral C₁₈₀(I_h), and C₂₄₀(I_h). We have obtained combinatorial tables for the isomers of C₁₈₀X_k and C₂₄₀X_k. Our results point to errors in previous computations on C₂₄₀ permutations. We have also outlined applications to NMR and ESR spectroscopy.     

A Strategy for Discovering Heterochiral Bioactive Peptides by Using the OB2nP Library and SPOTs Method

d -Amino acid containing peptides are promising as drug lead compounds because of their expected higher stability in vivo. A heterochiral random peptide library called the one-bead–2ⁿ-peptide (OB2ⁿP) library, which can display 2ⁿ peptide diastereomers per bead, has been developed. Through screening of the OB2ⁿP library and subsequent binding assay among the peptide diastereomers synthesized in parallel by means of the SPOTs method, new heterochiral mimotopes for the anti-β-endorphin monoclonal antibody have been obtained. One mimotope was a new ligand for the μ-opioid receptor. The screening strategy enabled d -amino acid containing drug leads to be obtained efficiently by expanding searchable chemical space without increasing the experimental scale.     

A fast branch,bound and remember algorithm for disassembly line balancing problem

In recent years, the interests of disassembly line have increased owing to economic reasons and the increase of environmental awareness. Effective line can provide many advantages in terms of economic aspect and it facilitates competition the companies with others. This study contributes to the relevant literature by a branch, bound and remember algorithm for disassembly line balancing problem with AND/OR precedence. The proposed exact solution method employs the memory-based dominance rule to eliminate the reduplicated sub-problems by storing all the searched sub-problems and to utilise cyclic best-first search strategy to obtain high-quality complete solutions fast. In this paper, minimising the number of stations is taken as the performance measure. The proposed methodology is tested on a set of 260 instances and compared with the mathematical model using CPLEX solver and five well-known metaheuristics. Computational results show that the proposed method is capable of obtaining the optimal solutions for all the tested instances with less than 0.1?seconds on average. Additionally, comparative study demonstrates that the proposed method is the state-of-the-art algorithm and outperforms the CPLEX solver and metaheuristics in terms of both solution quality and search speed aspects.     

A Dynamic Combinatorial Approach for Identifying Side Groups that Stabilize DNA-Templated Supramolecular Self-Assemblies

DNA-templated self-assembly is an emerging strategy for generating functional supramolecular systems, which requires the identification of potent multi-point binding ligands. In this line, we recently showed that bis-functionalized guanidinium compounds can interact with ssDNA and generate a supramolecular complex through the recognition of the phosphodiester backbone of DNA. In order to probe the importance of secondary interactions and to identify side groups that stabilize these DNA-templated self-assemblies, we report herein the implementation of a dynamic combinatorial approach. We used an in situ fragment assembly process based on reductive amination and tested various side groups, including amino acids. The results reveal that aromatic and cationic side groups participate in secondary supramolecular interactions that stabilize the complexes formed with ssDNA.     

常减压蒸馏装置换热网络的最优化

文章通过对某常减压装置的换热网络设计时的分析,提出最佳的网络优化方案。运用流程模拟软件在保证各侧线产品质量和收率的情况,通过对塔取热比例的优化,以尽可能提高换热终温;同时在不影响装置换热终温的前提下,尽可能的产生1.0 MPa蒸汽,大幅降低其他冷公用工程消耗,从而显著的降低装置的能耗。     

Control structure synthesis for operational optimization of mixed refrigerant processes for liquefied natural gas plant

The best control structures for the energy optimizing control of propane precooled mixed refrigerant (C₃MR) processes were examined. A first principles‐based rigorous dynamic model was developed to analyze the steady‐state and dynamic behaviors of the C₃MR process. The steady‐state optimality of the C₃MR process was then examined in a whole operation space for exploring the feasibility of the energy optimizing control for possible control structures. As a result, the temperature difference (TD) between the warm‐end inlet and outlet MR streams was exploited as a promising controlled variable to automatically keep the liquefaction process close to its optimum. The closed‐loop responses were finally evaluated for every possible control structure candidate. Based on the steady‐state optimality and the dynamic performance evaluation, several control structures with a TD loop were proposed to be most favorable for the energy optimizing control of the C₃MR process. The proposed optimality approach can be applied to any natural gas liquefaction process for determining a proper controlled variable for optimizing operation. © 2014 American Institute of Chemical Engineers AIChE J, 60: 2428–2441, 2014     

Optimal placement of metallic dampers for seismic upgrading of multistory buildings based on a cost‐effectiveness criterion using genetic algorithm

In this paper, an optimal placement methodology for metallic dampers is proposed to upgrade the seismic performance of multistory buildings. Most previous studies on optimal damper placement (ODP) problems have been focused on minimizing the seismic responses, whereas the present study aims to utilize the minimum total cost of dampers to achieve a prescribed level of seismic response. To this end, the optimization objective is constructed based on a cost‐effectiveness criterion, and the optimization constraint is defined based on a desired level of seismic response. An improved integer‐coded genetic algorithm is presented for solving the ODP problem. A 16‐story shear building is illustrated to verify the proposed optimal placement methodology. It is shown that the proposed methodology can be used to achieve the predetermined performance level while minimizing the retrofitting cost. Moreover, different algorithms, objective functions, and levels of accuracy on the optimization are also compared. Finally, a two‐step optimization approach is proposed for achieving better placement schemes with less computational efforts.     

基于生态位理论的城市空间优化策略研究——以增城市为例

土地利用担负着城市空间架构和空间优化的重要功能.从生态位的角度看,城市空间优化具有内在和外在两方面驱动力,分别是土地生态位扩充和土地生态位差.在内外两种驱动力的共同作用下,土地变化方向总是朝着效益最大化和生态适宜度最高的方向发展.根据土地生态位整体效益最大化原理,增城市城市空间优化应当采取以下策略:承接西南、充实中部、优化东部、平衡西部、联合南部、调控北部.     

双侧壁导坑隧道工法技术探讨

本文结合双侧壁导坑工法在广州市新光快速路新光隧道施工中的应用,指出不同条件下对双侧壁导坑施工工艺的引伸及拓展。